GLP-1 Protocols
Weight
Management.
The most effective metabolic tools available — with the clinical oversight they deserve.
What it is
GLP-1 receptor agonists are a class of compounds that mirror a hormone your gut already makes after meals. They tell your brain you’re satisfied, slow gastric emptying, and steady the blood-sugar swings that drive cravings.
For most members, the experience is quiet: less mental noise around food, smaller portions without effort, the kind of weight loss that’s slow and steady rather than performative.
“Your dosing should adjust to your body. Not the other way around.”
How it works
Your clinician selects the compound, starts you low, and titrates based on how your body responds — not a fixed calendar. Side effects (mild nausea, occasionally fatigue) usually fade within the first weeks; if they don’t, the dose drops back down.
Most members reach a therapeutic dose by month two. Cohort data is reviewed monthly with your provider so dosing stays paired to your labs and lived experience.
Compounds
Available in this protocol.
Semaglutide
0.25 → 2.4 mg / wk
The gold standard. Most studied. Weekly subcutaneous injection.
Tirzepatide
2.5 → 15 mg / wk
Dual GIP/GLP-1 receptor agonist. Stronger response in some patients.
Compound, dose, and frequency are determined by an independent licensed clinician.
The cohort
24h
from intake to clinician response
Cohort figures reflect aggregated, self-reported data from Loop members on this pathway. Individual results vary.
Important safety information
Loop Health is not a healthcare provider. Loop Health, LLC acts as a technology platform to connect you with independent, licensed healthcare providers (physicians and nurse practitioners) who evaluate your intake information and use their independent clinical judgment to determine whether treatment is medically appropriate for you.
Compounded medications are not FDA-approved. Compounded drugs, including compounded semaglutide and compounded tirzepatide, have not undergone FDA premarket review for safety, effectiveness, and quality. Compounding pharmacies are licensed and inspected by state Boards of Pharmacy.
Results may vary. Individual results vary significantly and depend on adherence to the treatment plan, diet, exercise, genetics, and health status. No specific outcomes are guaranteed.
Eligibility and availability. Available in select U.S. states where our provider partners are licensed to practice telemedicine. Must be 18 or older to qualify. We comply with HIPAA regulations.
Ready to start weight?
Five-minute intake. Clinician review within 24 hours. Protocol shipped to your door.